Genesis 27:41 And Esau hated Jacob because of the blessing wherewith his father blessed him: and Esau said in his heart, The days of mourning for my father are at hand; then will I slay my brother Jacob.
Jacob had deceived his father Isaac into giving him the greater blessing meant for Esau. This was a sin, but now it is what it is. In Esau’s eyes, God had shown favor to his brother. This is what mostly made him hate his brother, though also he hated him for his deceit and trickery. This reaction is very similar to the incident with Cain and his brother Abel: God favored and blessed one and left the other out; hatred began to simmer; such bitter resentment led to murder, or, at least in Esau’s case, the intention to murder. In both cases there was certainly some resentment toward God, for there always is (“Why? I don’t deserve this.”).
The sin is the same for both Esau and Cain: murder in the heart, ”Everyone who hates his brother is a murderer [1 John 3:15].” And Matthew 5:22: ”Everyone who is angry with his brother will be liable to judgment.” The meaning of the Commandment is this: hatred in the heart = murder. Esau is just as guilty of murder as Cain, even though he couldn’t carry it out, for Jacob fled.
The anger response is a warning to us. First, see it as murder. Second, repent and receive forgiveness instantly and constantly. Do not let the sun go down on your wrath. Anger/murder is a problem for all of us, but we have the Lord in us to lead us to repentance and faith. Cain and Esau were both exiled from God, as wanderers. Both could have stopped the consequences, but unfortunately did not.